Europe Size 46-16-135 to US: M
Cross-market adult eyewear and optical frame apparel conversion mapping 46-16-135 specifications into M.

Analyzing Size Equivalence Across Markets
Europe Size 46-16-135: Corresponds to a lens width baseline of 46 (1.81 ), bridge width of 16 , temple arm length of 135 , and fit classification Narrow / Petite Frame.
US: M: Corresponds to a lens width baseline of 52 (2.05 ), bridge width of 19 , temple arm length of 145 , and fit classification Standard / Regular Frame.